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Image Search Results
Journal: BMC Genomics
Article Title: RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs database
doi: 10.1186/s12864-018-5220-x
Figure Lengend Snippet: Comparison of pipelines analysis steps
Article Snippet: Using the RNA-Seq data from the rat miRNA body atlas, we developed user-friendly query interfaces to dynamically detect TE, TS and organ-specific (OS) miRNAs across three different bioinformatics pipelines (Data-Driven) based on 1)
Techniques: Comparison, Expressing
Journal: Cell systems
Article Title: Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States
doi: 10.1016/j.cels.2017.08.002
Figure Lengend Snippet: (I) Oncogenic activation signature is generated by experimentally expressing the oncogene of interest in an isogenic cell system. (II) The signature is decomposed using non-negative matrix factorization (NMF) using a reference dataset in order to generate transcriptional components. The components are optionally clustered or sub-selected to represent a specific sample population (e.g., KRAS mutants). (III) Cellular states are defined by clustering and an Onco-GPS map is generated. Samples are then projected onto the Onco-GPS map and further characterized by associating them to diverse genomic features.
Article Snippet: Decompose Signature and Generate Transcriptional Components The oncogenic signature defined above is decomposed using
Techniques: Activation Assay, Generated, Expressing